I stumbled upon a VRBO listing for this house by a complete accident and was not sure what to expect since we've never vacationed in South Carolina, let alone Daufuskie Island. And let me tell you, this place is a jem! The house is perfect to begin with, and the hosts made our stay absolutely worry-free! The check-in and check-out are super easy. We stay at VRBO-type places pretty much always, and this check-in/out was the easiest process we've experienced. We very much appreciated recommendations for the things to do, which were plenty. But we tried to take it easy and just enjoy our stay, and it was a success! Totally worth the travel (11 hrs by car, plus the ferry for us).
Dog friendliness is worth a separate paragraph. We usually leave our pooch behind because it is so hard to find a place that is dog friendly. I am happy to attest that the house and the entire island are very welcoming to dogs and it looks like the pups really have a grand time spending quality time with their families and all the "potential families" as ours did :)
Come to Daufuskie, stay at Tammy and Kurt's place, and tip well everywhere, it is absolutely worth it!
-Tanya and Justin (plus 3 kids and 1 dog) from NJ